August 4, 2010
DNA-vaccines are still untested and unsafe, but the Army is working to develop a new class of inoculations that can be rapidly developed and rapidly delivered to servicemen and civilians alike during times of outbreak or emergency.
The approach would utilize a gas-powered ‘gene-gun’ to blast multi-agent DNA-vaccines directly into cells without the use of needles, then stimulate the dosage with ‘electroporation,’ a technique the Army intends to become non-invasive but currently involves surgical exposure to muscle tissue. The mild shock can cause pain and tissue damage.
For gene gun delivery, DNA vaccines are coated onto microscopic gold beads and are deposited into skin cells by gas propulsion. Intramuscular electroporation involves injecting the DNA then quickly applying short electrical pulses to the delivery site. The electrical charge causes temporary pores to form in cellular membranes and facilitates uptake of the DNA vaccines. Electroporation has been found to greatly improve immune responses to DNA vaccines as compared to injection alone, and it allows for delivery of larger quantities of DNA in a single dose, making it suitable for multiagent vaccine delivery.
Central to the scheme is the combination of multiple-vaccine agents. The Army has solicited for the crystallization of the partially-tested vaccine applicator, which after meeting sufficient delivery design, must demonstrate “the combination of at least three DNA vaccines of interest to the military.” This indicates the likelihood that the number of vaccines given troops and the public would increase– a greater degree of medication to meet a ‘growing’ threat from genetically-engineered biological agents and pandemics.
It would also signal a new epoch of vaccinating the public. Thus-far untested synthetic-DNA strands would interact with the human body on a mass-scale for the first time, while the dosing of three or more strands would mark a strong interaction that could have unforeseen reactions in combination. Alternately, it would be more difficult to trace back dangerous vaccines based on symptoms developed after the fact when delivered together.
According to the Army, mastering the process would mean not only more quickly designed vaccinations, but a quicker interaction with the immune system. Further, dosing would be quicker because each recipient would not need a fresh needle, and the contact-free ‘gene gun’ would allow rapid person-to-person administration.
DNA vaccines can be rapidly engineered, readily combined and present minimal safety risks… the technology would also provide both civilian and military populations with a path toward rapid response to unknown, emerging, or genetically engineered pathogens.
Researchers have already exposed that vaccines represent a dangerous chemical interaction that cause brain damage, deadly auto-immune responses and more.
But Army vaccination plans aren’t just about disease resistance, it’s also about conditioning the ‘soldier of the future’– one pumped full of chemical ‘enhancements.’
The Daily Mail has reported on the development of inoculations to combat stress. “Academics say they are close to developing the first vaccine for stress – a single jab that would help us relax without slowing down.”
Similarly, the Pentagon has reportedly been investigating “pain vaccines” that would ideally “block the sense of pain for almost a month,” DARPA researcher Michael Goldblatt stated.
The military has also been eyeing “physical boosters” and “cognitive enhancers” to administer to troops through diet, pills or potentially vaccination delivery as well. The use of “Mitochondrial Energetics” to restore youthful vitality has been suggested, as has the use of modafinil, amphetimines and other stimulants to ‘keep pilots alert and awake’ during combat.
DARPA’s projection for the “Super Soldier of 2030″ includes the utilization of both “Cognitive enhancers” (nutritional, nootropic or other smart drugs) and “physical enhancers” (nutritional, pharmaceutical). “Consumer demand and scientific exploration will yield an explosion in cognitive and physical enhancers, including nootropic (smart) drugs, neural prosthetics, and permanent physical prosthetics,” the report states.
Military personnel are already pumped full of dozens of vaccines, and the perfection of the ‘gene gun’ would only put them one step closer to complete biological-and-chemical manipulation of the soldier.
This article was posted: Wednesday, August 4, 2010 at 11:29 am