California has adopted the toughest limits in the nation on the use of antibiotics in healthy livestock, barring their routine use to prevent illness or promote growth.

Calling the overuse of antibiotics “an urgent public health problem,” Gov. Jerry Brown announced Saturday he signed the legislation. The bill, SB 27, will curb the overuse of antibiotics in livestock, which limits the effectiveness of the medicines in both animals and people and contributes to the spread of dangerous, drug-resistant superbugs.

“The science is clear that the overuse of antibiotics in livestock has contributed to the spread of antibiotic resistance and the undermining of decades of life-saving advances in medicine,” Brown said in a statement.

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