Pregnant women should consider not traveling to the 2016 Olympic Games in Brazil due to the risk of Zika virus infection, the U.S. Centers for Disease Control and Prevention said on Friday.

CDC also said women considering becoming pregnant, and their male partners, should exercise caution if they travel to the Olympics or Paralympic Games, scheduled to take place in Rio de Janeiro in August and September.

“CDC Recommends that pregnant women consider not traveling to the Olympics,” the advisory says. “If you have a male partner who goes to the Olympics, you may be at risk for sexual transmission.”

CDC’s statement is the agency’s first explicit warning for some travelers to stay away from the Games in Rio de Janeiro, which has been expecting to draw as many as 400,000 tourists from around the world. Although the Olympics are still five months away, Brazilian authorities have been drawing up robust mosquito-control plans to minimize the risks to spectators and tourists alike.

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