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  • Lilly Sold Drug for Dementia Knowing It Didn’t Help

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    Margaret Cronin Fisk, Elizabeth Lopatto and Jef Feeley
    Bloomberg
    June 12, 2009

    Eli Lilly & Co. urged doctors to prescribe Zyprexa for elderly patients with dementia, an unapproved use for the antipsychotic, even though the drugmaker had evidence the medicine didn’t work for such patients, according to unsealed internal company documents.

    In 1999, four years after Lilly sent study results to the U.S. Food and Drug Administration showing Zyprexa didn’t alleviate dementia symptoms in older patients, it began marketing the drug to those very people, according to documents unsealed in insurer suits against the company for overpayment.

    • A d v e r t i s e m e n t
    • science technology   Lilly Sold Drug for Dementia Knowing It Didn’t Help
    Regulators required Lilly and other antipsychotic drug- makers in April 2005 to warn that the products posed an increased risk to elderly patients with dementia. The documents show the health dangers in marketing a drug for an unapproved use, called off-label promotion, said Sidney Wolfe, head of the health research group at Public Citizen in Washington.

    “By definition, off-label means there is no clear evidence that the benefits of a drug outweigh the risks,” Wolfe said. “The reason why off-label promotion is illegal is that you can greatly magnify the number of people who will be harmed.”

    In 1999, when Lilly began its marketing push, Zyprexa’s only approved use was for patients suffering from schizophrenia, according to the FDA. In 2008, Zyprexa was Lilly’s best-selling drug, with $4.7 billion in sales, while antipsychotics as a group topped U.S. drug sales last year, with $14.6 billion.

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    Comment Rules

    24 Responses to “Lilly Sold Drug for Dementia Knowing It Didn’t Help”

    1. "ren Says:

      holistic medicine is the way to go. big pharma is moneyminded. sad that the sheeple refuse to believe big pharma is out to wax em. i’ve never taken anything like antipsychotics but my brother in law did. we caught him out in our pasture 3:15 am mowing the dang corn. next day he didnt remember any of it. the proof was in mowed corn and a trashed out riding lawnmower…..funny now, but at the time…………..3:15am? we were pissed

      roaddog Reply:

      “ren—that sounds like some meth heads I used to know.

    2. AJ Vidz Says:

      HERE: Stream and Download ALL the best interviews and rants from the Alex Jones Show Archives:

      http://alex-jones-archives.politicsfiles.info/

      TODAY:

      - Cindy Sheehan:How The Left Used Me To Gain House Seats
      - Lew Rockwell:Obama’s Puppet Masters Have Been Busy
      - Dr. Walter Williams:The Rule of Law & Economics 101
      - Alex Jones Calls Glenn Beck Out!!

      Backup your favorite episodes, don’t miss any!

      12.160mhz Reply:

      Pharmaceutical companies are more dangerous to the people than any terrorist.

    3. roaddog Says:

      You would think that selling placebo’s would be illegal. I didn’t see anywhere in the article that charges were filed. Doctors kill 170,000 herd members a year by the wrong medications, botched surgery and misdiagnoses. I guess thats why they call it a “practice”.

      House Reply:

      LMAO!!! My FOURTH attempt to post here….will it make it?????

    4. House Says:

      Ren- That’s exactly the FDA is wanting control (regulation) of natural supplements. They’re good for you….how are you suppose to ingest poison by eating good things??

      Three atypical antipsychotics — Seroqiel, Geodon, and Zyprexa — were voted to be “acceptably safe” and effective for the treatment of schizophrenia and bipolar disorder in teenagers and children, said a U.S. Food and Drug Administration (FDA) panel of outside medical experts that reviews such indications for the FDA.

      http://psychcentral.com/news/2...../6457.html

    5. House Says:

      Since my 1st attempt at this evidently got “misplaced” in cyberspace (cough-BULLSHIT!)……………..

      Three atypical antipsychotics — Seroqiel, Geodon, and Zyprexa — were voted to be “acceptably safe” and effective for the treatment of schizophrenia and bipolar disorder in teenagers and children, said a U.S. Food and Drug Administration (FDA) panel of outside medical experts that reviews such indications for the FDA.

      http://psychcentral.com/news/2...../6457.html

      Gotta love the FDA…..this is why they want to regulate natural supplements…..not enough poison in them………..

      Bubba Johnson Reply:

      Um, it didn’t get “misplaced” in cyberspace. Cough-Bullshit!
      But, yeah, it does sometimes take a while to post after hitting send, whatever, give it time. Now if you really want to talk censorship, I posted once about Chinese women and their inability to do a certain sort of oral technique and it WAS censored. Cough.

    6. YELLOWHAK1 Says:

      i mean seriously, does any of this surprise anyone? you would have to be completely braindead to not know or just happy to be employed.

    7. jusnorm Says:

      my daughter is on med for autism. this is a fight i don’t like and don’t think the med works. i see her as a zombie. i want her body to fight this naturally but that is also a fight.

      segnosis Reply:

      I know what you are going through and I admire parents like you.

      check out this video….

      http://www.youtube.com/watch?v=KIjOZq_AUeE

    8. House Says:

      Lets see…..this will be my THIRD post here, and will contain nothing informative, so it will likely “make it”…………

    9. House Says:

      Fifth attempt to post….piece of shit site………….

    10. PrivateSi Says:

      Unsurprising giving the history of the FDA (and CDC for that matter)…

    11. segnosis Says:

      Most of these drugs mechanisms of action are unknown.

      Check out this video.
      http://www.youtube.com/watch?v=KIjOZq_AUeE

    12. PrivateSi Says:

      BBC:

      First UK swine flu patient death
      ———————————–

      Earlier this week, the public were urged to follow hygiene guidelines
      The swine flu virus has claimed its first victim in the UK, after a patient died in a Scottish hospital.

      The patient, who had underlying health problems, was one of 10 people being treated in the greater Glasgow area, said a Scottish government spokesman .
      The death is the first outside the Americas, where more than 140 people have died since the pandemic began.

      Swine flu has now infected almost 500 people in Scotland alone, out of 1,261 cases in the UK.
      Thirty-five new cases were confirmed on Sunday.

      A statement issued by the Scottish Government said: “With regret, we can confirm that one of the patients who had been in hospital, and had been confirmed as suffering from the H1N1 virus, has died today.

      I still think the chances of picking up the virus are remote
      Virologist Professor John Oxford

      “The patient had underlying health conditions.”

      The statement added that, at the family’s request, no further details will be released about the patient, whose gender, age and address remain unknown.

      Together with 61 new cases of swine flu in England and one case in Northern Ireland confirmed on Sunday, a total of 1,261 people have now caught the virus in the UK.
      Another 486 possible UK cases are being investigated…

      Rest of the article on the excellent BBC Website:

      I’d guess AIDS going by the lack of ‘further details’ – sorry to presume, I know it’s wrong but…

      Not sensationalised at least..

    13. Surfsup Says:

      Assisted living facilities, nursing homes routinely give all patients this drug.
      I learned this dealing with family.
      These places are owned by corporations. After so many day’s insurance and medicare will only pay so much at the end of that time you are paying up to two hundred a day. When you can no longer pay that they take your house your house.
      Didn’t get that far with our family we knew better. We asked a lot of questions. Demand to know everything about treatment.
      They compensate doctors that specialize in this kind of medicine. It’s all a win win.
      Big Pharma will crash just like the big 3.

    14. razor Says:

      How many waiters will spit in their food now that they know these low life pieces of crap never intended to help their Mom or Dad. Who knows, maybe a little TB sputum in the soup could do wonders for their demeanor.

    15. Big Bag Pharma Says:

      Take your meds my sheeple!!

      Meds are cool, hip, the thing to be on.

      Kids now put all these drugs in a bowl, then its party time.

      Pot Baa-aad!! Prozac good!!

    16. Adnil Says:

      I am a Psychiatric Nurse Practitioner who works with the elderly in long term care. Atypical
      antipsychotics, such as Zyprex are usefull to alleviate psychotic symptoms, such as hallucinations and delusions in dementia patients. When these symptoms are frightening, they can lead to combative behavior, refusing food, fluids, and assistance with care. In such cases the benefits do outweigh the risks as they improve quality of life and allow the demented elderly to be cared for in the least restrictive setting. The “off label” use of medications is common practice and justified when used to target specific problem symptoms.

    17. rachel Says:

      this is just the tip of the ice berg. I took an anti-depressant for inflammation and it nearly killed me. I have lapses in time. No one told me it was addictive and coming off it was horrific. I’m essentially a recovering drug addict now. I still crave the stuff and I have to be very careful on what the doctors give me. Since they use anti-depressants for things like sleeping pills, muscle relaxers and over active bladder.

      these meds are worse than crack and far more deadly IMHO. You do not get “high” on them like you would if you smoked a joint. Instead you become very complicit. Very suppressed and pretty much a lump on the couch. That’s if you have a good trip. Those who have a bad trip go out and kill themselves and everyone else.

      I don’t believe these anti-pych drugs stop hallucinations but merely suppresses the patient entirely.

    18. yellowhak1 Says:

      MSN “ZICAM WARNING STOP USING IT” STOP USING ALL NASAL SPRAYS. PERSONALLY I FEEL SYSTEMIC FUNGAL INFECTIONS ARE INTRODUCED THAT WAY BUT NO WAY OF BACKING IT UP THAT CLAIM.

    19. Anihilus Says:

      http://www.youtube.com/watch?v=G7X24_vOWwU