The 2018 Nobel Prize for Physiology or Medicine has been awarded to James Allison of the University of Texas and Tasuku Honjo of Japan’s Kyoto University for their discoveries in cancer therapy.

“Allison and Honjo showed how different strategies for inhibiting the brakes on the immune system can be used in the treatment of cancer,” the Nobel Assembly at Sweden’s Karolinska Institute said in a statement on awarding the prize.

The prize for physiology or medicine is first Nobel Prize awarded each year.

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