An intestinal illness carried by international travelers is spreading across the United States, according to the Centers for Disease Control and Prevention. The culprit bacteria have proven to be resistant to the antibiotic Cipro, most commonly prescribed to treat the infection.

Called Shigella, the bug turned up in 243 cases in 32 states and Puerto Rico between May and February, the CDC said in a statement today. The biggest clusters were reported in California, Massachusetts and Pennsylvania.

“These outbreaks show a troubling trend in Shigella infections in the United States,” CDC Director Tom Frieden said in the statement. “Drug-resistant infections are harder to treat and because Shigella spreads so easily between people, the potential for more—and larger—outbreaks is a real concern.”

Last week, President Barack Obama unveiled a national action plan to fight antibiotic resistance, a large and growing public health issue, and he designated $1.2 billion to fight drug-resistant bacteria in his most recent budget plan. The CDC says superbugs cause 2 million illnesses and 23,000 deaths each year in the U.S.

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