April 28, 2014
When it comes to the link between antidepressants and suicidal behavior in young people, dose may matter quite a bit, a new study suggests.
The Food and Drug Administration has for years required antidepressants to carry warnings that they may increase the risk of suicidal thinking and behavior in children and adults under age 25. The study, published online Monday by the journal JAMA Internal Medicine, finds the risk for deliberate self harm doubles when depressed young people start treatment with higher-than-usual doses.
The finding is one more reason for doctors and families to carefully consider how and whether to use the medications in young people, researchers say.