Elevated levels of trimethylamine N-oxide (TMAO) — a compound linked with the consumption of fish, seafood and a primarily vegetarian diet — may reduce hypertension-related heart disease symptoms. New research in rats finds that low-dose treatment with TMAO reduced heart thickening (cardiac fibrosis) and markers of heart failure in an animal model of hypertension.

The study is published ahead of print in the American Journal of Physiology — Heart and Circulatory Physiology and was chosen as an APSselect article for November.

TMAO levels in the blood significantly increase after eating TMAO-rich food such as fish and vegetables.

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