A knifeman has killed at least 19 people and injured 45 in Japan, according to local reports.

The attacker went into a centre for disabled people in Sagamihara, outside of Tokyo, brandishing a knife.

Police were called to the scene at around 2.30am local time after residents saw a man armed with a knife in the grounds of the Tsukui Yamayuri Garden.

Local media have reported that 19 people have died and 45 were injured – of which four are in a serious condition.

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