February 26, 2014

Advanced glycation endproducts, or AGEs, common in the “Western diet,” suppress levels of sirtuin, a key defense” against Alzheimer’s, U.S. researchers say.

Dr. Helen Vlassara, professor and director of the Division of Experimental Diabetes and Aging in the Brookdale Department of Geriatrics at Mount Sinai Icahn School of Medicine, found AGEs cause brain changes similar to Alzheimer’s disease and pre-diabetes.

AGEs, which naturally occur at low levels in the body, are found in high levels mostly in heat-processed animal food products, such as grilled or broiled meats — especially barbeque, Vlassara said.

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