The U.S. Supreme Court on Monday rejected a challenge by gun rights activists to a San Francisco regulation that requires gun owners to keep their weapons locked up or disabled when stored at home.

By declining to hear an appeal filed by gun owners and the National Rifle Association, the court left intact a March 2014 ruling by the San Francisco-based 9th U.S. Circuit Court of Appeals that upheld the measure.

The regulation, issued in 2007, states that anyone who keeps a handgun at home must either store it in a locked container or disable it with a trigger lock.

The challengers said the regulation violates the U.S. Constitution’s Second Amendment, which guarantees the right to bear arms.

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